Some of the medicinal properties of shiitake mushroom are attributed to a sugar molecule named lentinan, on which extensive research has been done. In laboratory tests, lentinan does not kill cancer cells directly, but enhances a number of aspects of the immune system, which may aid in the slowing of tumor growth. Lentinan also kills viruses and microbes directly in laboratory studies. Most studies of lentinan involve intravenous or intramuscular injections. It is uncertain whether the ingestion of shiitake mushrooms provides similar effects. One clinical trial has shown shiitake extract alone is not an effective treatment for prostate cancer.

Shiitake Mushroom

C$9.99

Forest mushroom

Lentinula

Pasania fungus

Hua gu
To prevent and treat cancer
A shiitake extract was found to be ineffective for the treatment of prostate cancer. However, an oral formulation of lentinan was shown effective in extending survival in patients with stomach, colorectal, pancreatic, and liver cancers. Larger studies are needed to confirm this effect.

To lower high cholesterol
Compounds in shiitake have cholesterol-lowering effects in lab studies, but there is no proof from clinical trials of their ability to also lower cholesterol in people.

To stimulate the immune system
Lentinan stimulates the activity of certain immune cells in lab studies and in people. However, it is unclear if lentinan or shiitake are effective in treating diseases such as AIDS and cancer.

To treat infections
Although lab studies suggest antiviral and antibacterial properties, clinical data are lacking.

Shiitake Mushroom

Common Names

Potential Benefits

Scientific Name